Can cutting out wheat really improve your mood?

Proteins in wheat , gluten and gliadin , can cause all sorts of problems that affect your mood .

That innocent looking loaf of bread in your kitchen might not be so innocent after all....

Here are 3 reasons to stop eating wheat today

  1. Tears your gut and impact serotonin levels Wheat contains gliadin which has been shown to increase gut permeability. In other words, gliadin tears a hole in your gut lining, compromising your gut function, triggering inflammation and letting food, that has not been broken down enough yet, leak into your bloodstream. Over 80% of serotonin, one of your feel good hormones, is made in the gut, so a damaged gut can damage your mood.

  2. Sends your mood off on a roller coaster Are you someone who just loves and craves bread? Wheat contains gluten which can attach to your opiate receptors, just like heroin, giving us a brief high followed by the inevitable crash.

  3. Causes inflammation and blackens our mood Wheat contains gluten, which if you are sensitive to it, can trigger ongoing inflammation in your body. The research linking inflammation to depression is growing fast .



  1. Casella G et all (Sep 2016) Mood disorders and non celiac gluten sensitivity Minerva Gastroenterol Dietol. . [Epub ahead of print]

  2. Bressan P1, Kramer P (Mar 2016) Bread and Other Edible Agents of Mental Disease. Front Hum Neurosci. ;10:130.

  3. Lister J et al (Jul 2015). Behavioral effects of food-derived opioid-like peptides in rodents: Implications for schizophrenia? Pharmacol Biochem Behav. ;134:70-8.

  4. Severance EG et al (May 2014) Seroreactive marker for inflammatory bowel disease and associations with antibodies to dietary proteins in bipolar disorder. Bipolar Disord.;16(3):230-40.

  5. Carr AC.(Nov 2012) Depressed mood associated with gluten sensitivity--resolution of symptoms with a gluten-free diet. N Z Med J. 125(1366):81-2.

  6. Cinova J et al (Jan 2011) Role of intestinal bacteria in gliadin-induced changes in intestinal mucosa: study in germ-free rats. PLoS One. 13;6(1)

  7. Sander GR et al.(Aug 2005) Rapid disruption of intestinal barrier function by gliadin involves altered expression of apical junctional proteins. FEBS Let, 2005; 579:4851-4855.

  8. Maes M et al. (Feb 2008) The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression. Neuroendocrinol Lett,; 29(1):117-124.

#mood #depression #gut #wheat

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